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Article

Rapid Detection of N-RAS Gene Common Mutations in Acute Myeloid Leukemia (AML) Using High Resolution Melting (HRM) Method.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2022

Zaka Khosravi Saeed, Moonesi Mohammadreza, Moradabadi Alireza, Rajaeinejad Mohsen, Heidari Mohammad Foad, Noroozi-Aghideh Ali

Abstract excerpt

OBJECTIVE: Acute myeloid leukemia is caused by the clonal proliferation of undifferentiated myeloid hematopoietic precursors. AML prognosis is highly involved in the treatment response and is determined by mutations in several genes such as N-RAS. This study aims to identify the distribution of common N-RAS mutations (codons 12, 13, and 61) in AML patients using the HRM method and confirm this method's efficiency...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35092380
DOI: 10.31557/APJCP.2022.23.1.125
PMCID: PMC9258652

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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