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Article

Fast and reliable mutation detection of the complete exon 11-15 JAK2 coding region using non-isotopic RNase cleavage assay (NIRCA).

European journal of haematology - 1 Sept 2009

Kambas Konstantinos, Mitroulis Ioannis, Kourtzelis Ioannis, Chrysanthopoulou Akrivi, Speletas Matthaios, Ritis Konstantinos

Abstract excerpt

The screening for JAK2 V617F mutation in patients with polycythemia vera, essential thrombocythemia, and idiopathic myelofibrosis offers crucial information for the final diagnosis of these disorders. Recently, several JAK2 exons 12 and 14 mutations have been detected in V617F-negative patients with idiopathic erythrocytosis. The need for a rapid and accurate assay for the mutation screening in both exons 12 and...

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Source

Identifiers

PMID: 19500139
DOI: 10.1111/j.1600-0609.2009.01279.x

Genes

JAK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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