Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Localized reduction of atherosclerosis in von Willebrand factor-deficient mice.

Blood - 1 Sept 2001

Methia N, André P, Denis C V, Economopoulos M, Wagner D D

Abstract excerpt

To examine the role of the platelet adhesion molecule von Willebrand factor (vWf) in atherogenesis, vWf-deficient mice (vWf-/-) were bred with mice lacking the low-density lipoprotein receptor (LDLR-/-) on a C57BL/6J background. LDLR-/-vWf+/+ and LDLR-/-vWf-/- mice were placed on a diet rich in saturated fat and cholesterol for different lengths of time. The atherogenic diet stimulated leukocyte rolling in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aortic Diseases
Share to Arteriosclerosis
Share to Chemotaxis, Leukocyte

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Diet, Atherogenic

Share to Integrin beta3

Share to Platelet Membrane Glycoproteins

Share to von Willebrand Diseases

Share to von Willebrand Factor

Source

Identifiers

PMID: 11520791
DOI: 10.1182/blood.v98.5.1424

Genes

LDLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Localized reduction of atherosclerosis in von Willebrand factor-deficient mice.PMID 11520791Read ↗

A fibrinogen deficiency accelerates the initiation of LDL cholesterol-driven atherosclerosis via thrombin generation and platelet activation in genetically predisposed mice.Semantic proximity Read ↗

Novel insights into the development of atherosclerosis in hemophilia A mouse models.Semantic proximity Read ↗

Deficiency of inflammatory cell adhesion molecules protects against atherosclerosis in mice.Semantic proximity Read ↗

Deficiency of LRP1 in Mature Adipocytes Promotes Diet-Induced Inflammation and Atherosclerosis-Brief Report.Semantic proximity Read ↗

Peroxiredoxin1 prevents excessive endothelial activation and early atherosclerosis.Semantic proximity Read ↗

Atherosclerotic lesions grow through recruitment and proliferation of circulating monocytes in a murine model.Semantic proximity Read ↗

A major role for VCAM-1, but not ICAM-1, in early atherosclerosis.Semantic proximity Read ↗

Platelet CD36 links hyperlipidemia, oxidant stress and a prothrombotic phenotype.Semantic proximity Read ↗

Genetic Ablation of Caveolin-1 Confers Protection Against AtherosclerosisSemantic proximity Read ↗

Genetic Ablation of <i>Adamts13</i> Gene Dramatically Accelerates the Formation of Early Atherosclerosis in a Murine ModelSemantic proximity Read ↗

Molecular imaging of activated von Willebrand factor to detect high-risk atherosclerotic phenotype.Semantic proximity Read ↗

Plasminogen deficiency accelerates vessel wall disease in mice predisposed to atherosclerosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.