Article
Deficiency of inflammatory cell adhesion molecules protects against atherosclerosis in mice.
Arteriosclerosis, thrombosis, and vascular biology - 1 Aug 1997
Nageh M F, Sandberg E T, Marotti K R, Lin A H, Melchior E P, Bullard D C, Beaudet A L
Abstract excerpt
Leukocyte and endothelial cell adhesion molecules (CAMs) are essential for emigration of leukocytes, with the selectins mediating the initial step of leukocyte "rolling" and the beta 2-(CD18) integrins and intercellular adhesion molecule-1 (ICAM-1) being important for firm adhesion and emigration. On the basis of evidence for an inflammatory component in the pathogenesis of atherosclerosis, including increased...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
