Article
Deficiency of inflammatory cell adhesion molecules protects against atherosclerosis in mice.
Arteriosclerosis, thrombosis, and vascular biology - 1 Aug 1997
Nageh M F, Sandberg E T, Marotti K R, Lin A H, Melchior E P, Bullard D C, Beaudet A L
Abstract excerpt
Leukocyte and endothelial cell adhesion molecules (CAMs) are essential for emigration of leukocytes, with the selectins mediating the initial step of leukocyte "rolling" and the beta 2-(CD18) integrins and intercellular adhesion molecule-1 (ICAM-1) being important for firm adhesion and emigration...
Topics
- Animal Feed
- Animals
- Arteriosclerosis
- CD18 Antigens
- Cholesterol, Dietary
- Dietary Fats
- Disease Susceptibility
- Female
- Gene Expression
- Homozygote
- Intercellular Adhesion Molecule-1
- Leukocyte-Adhesion Deficiency Syndrome
- Lipids
- Mice
- Mice, Inbred C57BL
- Mutation
- P-Selectin