Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Atherosclerotic lesions grow through recruitment and proliferation of circulating monocytes in a murine model.

The American journal of pathology - 1 Jun 2002

Lessner Susan M, Prado Heather L, Waller Edmund K, Galis Zorina S

Abstract excerpt

Macrophage-derived foam cells in developing atherosclerotic lesions may potentially originate either from recruitment of circulating monocytes or from migration of resident tissue macrophages. In this study, we have determined the source of intimal macrophages in the apoE-knockout mouse flow-cessation/hypercholesterolemia model of atherosclerosis using a bone marrow transplantation approach. We also examined the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arteriosclerosis
Share to Carotid Arteries

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Foam Cells

Share to Intercellular Adhesion Molecule-1

Share to Leukocyte Common Antigens

Share to P-Selectin

Share to Platelet Endothelial Cell Adhesion Molecule-1

Share to Vascular Cell Adhesion Molecule-1

Source

Open in PubMed Open full text

Identifiers

PMID: 12057918
DOI: 10.1016/S0002-9440(10)61163-7
PMCID: PMC1850830

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Atherosclerotic lesions grow through recruitment and proliferation of circulating monocytes in a murine model.PMID 12057918Read ↗

Inflammatory cell recruitment in cardiovascular disease: murine models and potential clinical applicationsSemantic proximity Read ↗

Smooth Muscle Cells in Atherosclerosis Originate From the Local Vessel Wall and Not Circulating Progenitor Cells in ApoE Knockout MiceSemantic proximity Read ↗

CXCL12 promotes the stabilization of atherosclerotic lesions mediated by smooth muscle progenitor cells in Apoe-deficient mice.Semantic proximity Read ↗

Novel Role of Endothelial CD45 in Regulating Endothelial-to-Mesenchymal Transition in AtherosclerosisSemantic proximity Read ↗

The Greatly Under-Represented Role of Smooth Muscle Cells in AtherosclerosisSemantic proximity Read ↗

Leukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues.Semantic proximity Read ↗

Endothelial-to-Mesenchymal Transition in Atherosclerosis: Friend or Foe?Semantic proximity Read ↗

Lineage tracing of cells involved in atherosclerosis.Semantic proximity Read ↗

Foam cell formation: A new target for fighting atherosclerosis and cardiovascular disease.Semantic proximity Read ↗

Local M-CSF (Macrophage Colony-Stimulating Factor) Expression Regulates Macrophage Proliferation and Apoptosis in AtherosclerosisSemantic proximity Read ↗

Hypercholesterolemia-induced priming of hematopoietic stem and progenitor cells aggravates atherosclerosis.Semantic proximity Read ↗

Inflammatory Ly6Chi monocytes and their conversion to M2 macrophages drive atherosclerosis regression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.