Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Streptococcal pyrogenic exotoxin B enhances tissue damage initiated by other Streptococcus pyogenes products.

The Journal of infectious diseases - 15 Sept 2001

Saouda M, Wu W, Conran P, Boyle M D

Abstract excerpt

This study compared the pathology and infection pattern of streptococcal pyrogenic exotoxin B-positive (SpeB(+)) and SpeB-negative (SpeB(-)) isogenic variants of an M1 isolate of Streptococcus pyogenes in a mouse skin air sac model. SpeB(+) strains resulted in severe local tissue damage that exte...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Northern
Share to Epidermis
Share to Exotoxins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Bacterial

Share to Muscle, Skeletal

Share to Streptococcal Infections

Share to Streptococcus pyogenes

Source

Identifiers

PMID: 11517433
DOI: 10.1086/323083

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11517433-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Streptococcal pyrogenic exotoxin B enhances tissue damage initiated by other Streptococcus pyogenes products.PMID 11517433Read ↗

Role of streptococcal pyrogenic exotoxin B in the mouse model of group A streptococcal infection.Semantic proximity Read ↗

Molecular analysis of the role of streptococcal pyrogenic Exotoxin A (SPEA) in invasive soft-tissue infection resulting from Streptococcus pyogenes.Semantic proximity Read ↗

Inactivation of Streptococcus pyogenes extracellular cysteine protease significantly decreases mouse lethality of serotype M3 and M49 strains.Semantic proximity Read ↗

Streptococcal Cysteine Protease-Mediated Cleavage of Desmogleins Is Involved in the Pathogenesis of Cutaneous Infection.Semantic proximity Read ↗

Toxoids of streptococcal pyrogenic exotoxin A are protective in rabbit models of streptococcal toxic shock syndrome.Semantic proximity Read ↗

Proinflammatory synergy between protease and superantigen streptococcal pyogenic exotoxinsSemantic proximity Read ↗

Streptococcal pyrogenic exotoxin B inhibits apoptotic cell clearance by macrophages through protein S cleavage.Semantic proximity Read ↗

Selective Modulation of Superantigen‐Induced Responses by Streptococcal Cysteine ProteaseSemantic proximity Read ↗

Analysis of the superantigenic activity of mutant and allelic forms of streptococcal pyrogenic exotoxin A.Semantic proximity Read ↗

Mouse skin passage of a Streptococcus pyogenes Tn917 mutant of sagA/pel restores virulence, beta-hemolysis and sagA/pel expression without altering the position or sequence of the transposon.Semantic proximity Read ↗

Contribution of Secreted NADase and Streptolysin O to the Pathogenesis of Epidemic Serotype M1 Streptococcus pyogenes Infections.Semantic proximity Read ↗

A two-component regulatory system, CsrR-CsrS, represses expression of three Streptococcus pyogenes virulence factors, hyaluronic acid capsule, streptolysin S, and pyrogenic exotoxin B.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.