Article
Stereotypic behaviors in mice selectively bred for high and low methamphetamine-induced stereotypic chewing.
Psychopharmacology - 1 Aug 2001
Atkins A L, Helms M L, O'Toole L A, Belknap J K
Abstract excerpt
RATIONALE: At high doses, methamphetamine produces repetitive stereotypic behaviors, and the degree to which this occurs is heritable. OBJECTIVES: Mice of a B6D2F2 genetic background were selectively bred for four generations for high (HMA) and low (LMA) numbers of stereotyped chewing episodes measured for 1 min at 33 min post-injection following 10 mg/kg methamphetamine (changed to 7 mg/kg for the high line and...
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