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Article

Drug reward and intake in lines of mice selectively bred for divergent exploration of a hole board apparatus.

Genes, brain, and behavior - 1 Oct 2007

Kliethermes C L, Kamens H M, Crabbe J C

Abstract excerpt

Individuals characterized as high-novelty seekers are more likely to abuse drugs than are low-novelty seekers, and it is possible that the biological substrates underlying novelty seeking and drug abuse are similar. We selectively bred replicate lines of mice from a B6D2 F3 hybrid stock for high exploratory behavior (HEB) or low exploratory behavior (LEB) as measured by the number of head dips on a hole board. To...

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Identifiers

PMID: 17147699
DOI: 10.1111/j.1601-183X.2006.00289.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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