Article
Selective breeding for magnitude of methamphetamine-induced sensitization alters methamphetamine consumption.
Psychopharmacology - 1 Apr 2011
Scibelli Angela C, McKinnon Carrie S, Reed Cheryl, Burkhart-Kasch Sue, Li Na, Baba Harue, Wheeler Jeanna M, Phillips Tamara J
Abstract excerpt
RATIONALE: Genetically determined differences in susceptibility to drug-induced sensitization could be related to risk for drug consumption. OBJECTIVES: Studies were performed to determine whether selective breeding could be used to create lines of mice with different magnitudes of locomotor sensitization to methamphetamine (MA). MA sensitization (MASENS) lines were also examined for genetically correlated...
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