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Article

Sensitization to stereotypy in DBA/2J but not C57BL/6J mice with repeated cocaine.

Pharmacology, biochemistry, and behavior - 1 May 1994

Tolliver B K, Carney J M

Abstract excerpt

The present study investigated the effects of seven repeated daily injections of 32 mg/kg cocaine on stereotyped behaviors (repetitive locomotion, rearing, and head bobbing) in two genetically distinct strains of mice. An initial injection of cocaine induced no stereotypy in either DBA/2J or C57BL/6J mice. Following the fourth daily injection, cocaine induced stereotypies in DBA/2J mice (11.33 +/- 4.40) compared...

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PMID: 8029287
DOI: 10.1016/0091-3057(94)90513-4

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