Article
Genotypic variation of HIV-1 reverse transcriptase and protease: comparative analysis of clade C and clade B.
AIDS (London, England) - 17 Aug 2001
Grossman Z, Vardinon N, Chemtob D, Alkan M L, Bentwich Z, Burke M, Gottesman G, Istomin V, Levi I, Maayan S, Shahar E, Schapiro J M
Abstract excerpt
OBJECTIVE: To compare drug-resistant variants from untreated (naive) and treated patients infected with clade B or C virus. METHODS: Consecutive samples (165) from patients throughout Israel were analyzed. All those in the treated group were failing highly active antiretroviral therapy. RESULTS: There were 87 clade B (14 naive) and 78 clade C (20 naive) [corrected] with significant differences in the prevalence...
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