Article
Testing genotypic and phenotypic resistance in human immunodeficiency virus type 1 isolates of clade B and other clades from children failing antiretroviral therapy.
Journal of clinical microbiology - 1 Dec 2002
Brindeiro Patrícia A, Brindeiro Rodrigo M, Mortensen Cláudio, Hertogs Kurt, De Vroey Veronique, Rubini Norma P M, Sion Fernando S, De Sá Carlos A M, Machado Deisy M, Succi Regina C M, Tanuri Amilcar
Abstract excerpt
The emergence of resistance to antiretroviral drugs is a major obstacle to the successful treatment of human immunodeficiency virus type 1 (HIV-1)-infected patients. In this work, we correlate clinical and virological trends such as viral load (VL) and CD4 counts to genotypic and phenotypic antiretroviral (ARV) resistance profiles of HIV-1 isolates from the B and non-B subtypes found in vertically infected...
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