Article
Genotypic analysis of the protease and reverse transcriptase of non-B HIV type 1 clinical isolates from naïve and treated subjects.
Antiviral research - 1 Aug 2009
Monno Laura, Scudeller Luigia, Brindicci Gaetano, Saracino Annalisa, Punzi Grazia, Chirianni Antonio, Lagioia Antonella, Ladisa Nicoletta, Lo Caputo Sergio, Angarano Gioacchino
Abstract excerpt
One hundred and ninety-two pol sequences of drug-naïve and drug-experienced subjects infected with non-B HIV-1 subtypes were analyzed to identify treatment-related amino acid changes which might be relevant for drug-resistance and possibly not included in the accepted mutation list for the B subtype. The correspondence analysis identified non-B-specific and subtype-specific polymorphisms which should not be...
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