Article
Genotypic analysis of the protease and reverse transcriptase of non-B HIV type 1 clinical isolates from naïve and treated subjects.
Antiviral research - 1 Aug 2009
Monno Laura, Scudeller Luigia, Brindicci Gaetano, Saracino Annalisa, Punzi Grazia, Chirianni Antonio, Lagioia Antonella, Ladisa Nicoletta, Lo Caputo Sergio, Angarano Gioacchino
Abstract excerpt
One hundred and ninety-two pol sequences of drug-naïve and drug-experienced subjects infected with non-B HIV-1 subtypes were analyzed to identify treatment-related amino acid changes which might be relevant for drug-resistance and possibly not included in the accepted mutation list for the B subt...
Topics
- Adult
- Anti-HIV Agents
- DNA Mutational Analysis
- Female
- Genotype
- HIV Infections
- HIV Protease
- HIV Reverse Transcriptase
- HIV-1
- Humans
- Male
- Middle Aged
- Mutation, Missense
- Polymorphism, Genetic
- RNA, Viral
