Article
Nucleotide and amino acid polymorphisms at drug resistance sites in non-B-subtype variants of human immunodeficiency virus type 1.
Antimicrobial agents and chemotherapy - 1 Aug 2004
Turner Dan, Brenner Bluma, Moisi Daniela, Detorio Mervi, Cesaire Raymond, Kurimura Takashi, Mori Haruyo, Essex Max, Maayan Shlomo, Wainberg Mark A
Abstract excerpt
We have compared nucleotide substitutions and polymorphisms at codons known to confer drug resistance in subtype B strains of human immunodeficiency virus type 1 (HIV-1) with similar substitutions in viruses of other subtypes. Genotypic analysis was performed on viruses from untreated individuals. Nucleotide and amino acid diversity at resistance sites was compared with a consensus subtype B reference virus....
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