Article
Mediation of tubuloglomerular feedback by adenosine: evidence from mice lacking adenosine 1 receptors.
Proceedings of the National Academy of Sciences of the United States of America - 14 Aug 2001
Sun D, Samuelson L C, Yang T, Huang Y, Paliege A, Saunders T, Briggs J, Schnermann J
Abstract excerpt
Adenosine is a determinant of metabolic control of organ function increasing oxygen supply through the A2 class of adenosine receptors and reducing oxygen demand through A1 adenosine receptors (A1AR). In the kidney, activation of A1AR in afferent glomerular arterioles has been suggested to contribute to tubuloglomerular feedback (TGF), the vasoconstriction elicited by elevations in [NaCl] in the macula densa...
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