Article
Functional consequences at the single-nephron level of the lack of adenosine A1 receptors and tubuloglomerular feedback in mice.
Pflugers Archiv : European journal of physiology - 1 May 2004
Vallon V, Richter K, Huang D Y, Rieg T, Schnermann J
Abstract excerpt
Mice deficient for adenosine A1 receptors (A1AR) lack tubuloglomerular feedback (TGF). In vivo micropuncture experiments were performed under anesthesia in A1AR-deficient and wild-type littermate mice to study the effects of chronic absence of A1AR on fluid and Na(+) reabsorption along the nephro...
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