Article
A novel inducible expression system to study transdominant mutants of HIV-1 Vpr.
Virology - 15 Aug 2001
Zhou Y, Ratner L
Abstract excerpt
In this study, an episomal system for ecdysone-inducible gene expression was developed. Human embryonic kidney 293 cells (293VE) expressing a heterodimer of modified ecdysone and retinoid X receptors and the Epstein-Barr nuclear antigen-1 were screened. Plasmids containing the EBV replication origin, oriP, and the ecdysone-response element could replicate and persist in 293VE cells to inducibly express luciferase...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
