Article
A transdominant tat mutant that inhibits tat-induced gene expression from the human immunodeficiency virus long terminal repeat.
Proceedings of the National Academy of Sciences of the United States of America - 1 Jul 1990
Pearson L, Garcia J, Wu F, Modesti N, Nelson J, Gaynor R
Abstract excerpt
Regulation of human immunodeficiency virus (HIV) gene expression is dependent on specific regulatory regions in the long terminal repeat. These regions include the enhancer, SP1, "TATA," and trans-activating (TAR) regions. In addition, viral regulatory proteins such as tat and rev are important i...
Topics
- Amino Acid Sequence
- Base Sequence
- Fluorescent Antibody Technique
- Gene Expression Regulation, Viral
- Gene Products, tat
- Genes, Dominant
- Genes, Viral
- HIV
- HeLa Cells
- Humans
- Molecular Sequence Data
- Mutation
- Repetitive Sequences, Nucleic Acid
- Restriction Mapping