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Article

Evidence for Vpr-dependent HIV-1 replication in human CD4+ CEM.NKR T-cells.

Retrovirology - 7 Nov 2012

Zhou Tao, Dang Ying, Baker Jacob J, Zhou Jiajun, Zheng Yong-Hui

Abstract excerpt

BACKGROUND: Vpr is exclusively expressed in primate lentiviruses and contributes to viral replication and disease progression in vivo. HIV-1 Vpr has two major activities in vitro: arrest of cell cycle in the G2 phase (G2 arrest), and enhancement of viral replication in macrophages. Previously, we...

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Share to CD4-Positive T-Lymphocytes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Serine-Threonine Kinases

Share to Ubiquitin-Protein Ligases

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Share to vpr Gene Products, Human Immunodeficiency Virus

Source

Open in PubMed Open full text

Identifiers

PMID: 23134572
DOI: 10.1186/1742-4690-9-93
PMCID: PMC3528630

Genes

DCAF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23134572-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

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Evidence for Vpr-dependent HIV-1 replication in human CD4+ CEM.NKR T-cells.PMID 23134572Read ↗

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