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Article

Conformation of the C-terminal domain of the pro-apoptotic protein Bax and mutants and its interaction with membranes.

Biochemistry - 21 Aug 2001

del Mar Martínez-Senac M, Corbalán-García S, Gómez-Fernández J C

Abstract excerpt

The C-terminal domain of the pro-apoptotic protein Bax is a hydrophobic stretch which, it has been predicted, anchors this protein to the outer mitochondrial membrane when apoptosis is induced in the cell. A 21mer peptide imitating this domain has been synthesized together with two mutants, one with a S184 substituted by K and the other with the S184 deleted. When their structures were studied by infrared...

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Identifiers

PMID: 11502195
DOI: 10.1021/bi010667d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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