Article

Computational design of Bax-inhibiting peptides

2024-10-31

Abstract excerpt

The proteins of the Bcl-2 family play crucial roles in regulating apoptosis. It is divided into pro-survival and pro-apoptotic proteins that determine cellular fate. In particular, Bax is a crucial executor of apoptosis as its activation initiates the apoptotic phenotype. Hence, targeting this protein represents an attractive therapeutic approach, which can aid in regulating apoptotic signalling and potentially co...

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Literature Corpus work: ccc0fb10-9e4a-5be4-8dfa-baa77f77a064
DOI: 10.1101/2024.10.28.617283

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