Article
p38beta MAP kinase protects rat mesangial cells from TNF-alpha-induced apoptosis.
Journal of cellular biochemistry - 1 Jan 2001
Guo Y L, Kang B, Han J, Williamson J R
Abstract excerpt
p38 MAP kinases (p38) and c-Jun N-terminal protein kinases (JNK) have been associated with TNF-alpha-induced apoptosis. However, recent studies indicate that an early but brief activation of JNK and/or p38 may actually protect some cells from TNF-alpha-induced apoptosis. Whether the activation of JNK and p38 provides a pro- or anti-apoptotic signal for TNF-alpha has been controversial. In this study, we...
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