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Article

Werner syndrome: genetic and molecular basis of a premature aging disorder.

Cellular and molecular life sciences : CMLS - 1 Jun 2001

Lebel M

Abstract excerpt

Werner syndrome (WS) is a rare autosomal recessive disorder characterized by genomic instability and by the premature onset of a number of age-related diseases, including cancers. The gene responsible for WS encodes a protein that has an exonuclease domain and a domain similar to DNA helicases of the RecQ-like subfamily. Accumulating evidence indicates that the WS gene product is involved in resolving aberrant...

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Identifiers

PMID: 11497235
DOI: 10.1007/s00018-001-8398-y
PMCID: PMC11337369

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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