Article
Association of an interleukin-1beta genetic polymorphism with altered brain structure in patients with schizophrenia.
The American journal of psychiatry - 1 Aug 2001
Meisenzahl E M, Rujescu D, Kirner A, Giegling I, Kathmann N, Leinsinger G, Maag K, Hegerl U, Hahn K, Möller H J
Abstract excerpt
OBJECTIVE: This study investigated the effect on brain morphology of an interleukin-1beta genetic polymorphism (C-->T transition at position -511) in patients with schizophrenia. METHOD: In vivo magnetic resonance imaging and genotype analysis were used in the examination of 44 male schizophrenic patients and 48 healthy male comparison subjects. RESULTS: No association between the interleukin-1beta polymorphism...
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