Article
Gray matter deficits in bipolar disorder are associated with genetic variability at interleukin-1 beta gene (2q13).
Genes, brain, and behavior - 1 Oct 2008
Papiol S, Molina V, Desco M, Rosa A, Reig S, Sanz J, Palomo T, Fañanás L
Abstract excerpt
Twin, family and recent molecular studies support the hypothesis of genetic overlapping between schizophrenia and bipolar disorder. Brain structural features shared by both psychiatric disorders might be the phenotypic expression of a common genetic risk background. Interleukin-1 (IL-1) cluster (chromosome 2q13) genetic variability, previously associated with an increased risk both for schizophrenia and for...
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