Article
Heritability of BDNF alleles and their effect on brain morphology in schizophrenia.
American journal of medical genetics - 15 Dec 1999
Wassink T H, Nelson J J, Crowe R R, Andreasen N C
Abstract excerpt
Accumulating evidence suggests that disturbed brain development may play a role in the etiology of schizophrenia, and that the illness is, to a significant degree, heritable. We therefore investigated brain derived neurotrophic factor (BDNF), a neurotrophin expressed in fetal brain, as a candidate disease gene for schizophrenia. We also investigated the effect of BDNF on adult brain morphology. All subjects were...
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