Article
Effect of the interleukin-1β gene on dorsolateral prefrontal cortex function in schizophrenia: a genetic neuroimaging study.
Biological psychiatry - 1 Nov 2012
Fatjó-Vilas Mar, Pomarol-Clotet Edith, Salvador Raymond, Monté Gemma C, Gomar Jesús J, Sarró Salvador, Ortiz-Gil Jordi, Aguirre Candibel, Landín-Romero Ramón, Guerrero-Pedraza Amalia, Papiol Sergi, Blanch Josep, McKenna Peter J, Fañanás Lourdes
Abstract excerpt
BACKGROUND: Genetic studies have found that the interleukin-1β gene (IL1B, 2q13) influences the risk for schizophrenia, but the underlying biological mechanisms of the association are still unclear. Investigation of the effects of genetic variability in this gene on brain function could provide more information about its role in the disorder. METHODS: The present study examined the effects of a functional...
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