Article
Genetic determinants of ethanol-induced liver damage.
Molecular medicine (Cambridge, Mass.) - 1 Apr 2001
Monzoni A, Masutti F, Saccoccio G, Bellentani S, Tiribelli C, Giacca M
Abstract excerpt
BACKGROUND: Although a clear correlation exists between cumulative alcohol intake and liver disease, only some of the alcohol abusers develop signs of ethanol-induced liver damage. To identify some of the genetic variations predisposing persons to alcoholic liver disease (ALD), a genetic study was performed in heavy drinkers from the cohort of the Dionysis study, a survey aimed at evaluating liver disease in the...
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