Genetic polymorphism of alcohol dehydrogenase 3 in digestive tract alcohol damage.

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Article

Genetic polymorphism of alcohol dehydrogenase 3 in digestive tract alcohol damage.

Hepato-gastroenterology - 1 Jun 2007

Cichoz-Lach H, Partycka J, Nesina I, Wojcierowski J, Słomka M, Celiński K

Abstract excerpt

BACKGROUND/AIMS: Genetic polymorphism of enzymes involved in alcohol metabolism plays a relevant role in etiopathogenesis of alcohol disease. The aim of the present study was to find in the Polish population the ADH3 genotypes, which are likely to be responsible for higher susceptibility to alcohol disease of the liver and chronic alcohol pancreatitis. METHODOLOGY: The ADH3 genotype and ADH3*1 and ADH3*2 alleles...

Topics

Adult
Alcohol Dehydrogenase
Alcoholism
Ethanol
Female
Genetic Predisposition to Disease
Humans
Liver Cirrhosis, Alcoholic
Male
Middle Aged
Pancreatitis, Alcoholic
Poland
Polymorphism, Genetic
White People

Source

Open in PubMed

Identifiers

PMID: 17629074

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