Article
Genetic determinants of alcohol addiction and metabolism: a survey in Italy.
Alcoholism, clinical and experimental research - 1 Feb 2001
Pastorelli R, Bardazzi G, Saieva C, Cerri A, Gestri D, Allamani A, Airoldi L, Palli D
Abstract excerpt
BACKGROUND: Although multiple genes are involved in alcoholism and can contribute differently to the risk of dependence and liver damage, no studies have investigated susceptibility to addiction in combination with susceptibility to liver damage due to differences in ethanol metabolism. METHODS: We evaluated the role of three polymorphic genes related to alcohol metabolism (CYP2E1) and, possibly, dependence (DRD2...
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