Article
[Activation of K-ras and c-erbB-2 protooncogenes in human colonic adenocarcinomas].
Acta gastroenterologica Latinoamericana - 1 May 2001
Golijow C, Güerci A, Mourón S, Abba M, Dulout F N, Ottino A, Pianzola H
Abstract excerpt
Although data on genetic alterations leading to development of colorectal cancer are abundant, no specific genetic alteration has been demonstrated for each class of tumor. The colorectal cancer phenotype is originated from an accumulation of different genetic alterations. The nature of these alterations, their order of appearance, and their associations vary greatly from one tumor to another, suggesting that the...
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