Article
Oligoclonal T cell proliferation in patients with rheumatoid arthritis and their unaffected siblings.
Arthritis and rheumatism - 1 Jun 1996
Waase I, Kayser C, Carlson P J, Goronzy J J, Weyand C M
Abstract excerpt
OBJECTIVE: To analyze whether patients with rheumatoid arthritis (RA) have an intrinsic defect in T cell proliferation and survival, possibly contributing to the infiltration of the synovial membrane with CD4+ T cells. METHODS: Fifteen patients with seropositive RA, 11 patients with psoriatic arthritis, 20 normal controls, and 9 affected and 13 unaffected siblings from 7 multiplex families with RA were analyzed...
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