Article
Oligoclonal T cell proliferation in patients with rheumatoid arthritis and their unaffected siblings.
Arthritis and rheumatism - 1 Jun 1996
Waase I, Kayser C, Carlson P J, Goronzy J J, Weyand C M
Abstract excerpt
OBJECTIVE: To analyze whether patients with rheumatoid arthritis (RA) have an intrinsic defect in T cell proliferation and survival, possibly contributing to the infiltration of the synovial membrane with CD4+ T cells. METHODS: Fifteen patients with seropositive RA, 11 patients with psoriatic art...
Topics
- Adult
- Aged
- Arthritis, Rheumatoid
- Base Sequence
- CD4-Positive T-Lymphocytes
- Cell Division
- Cell Size
- Clone Cells
- Family
- Humans
- Immunity, Cellular
- Lymphocyte Activation
- Middle Aged
- Molecular Sequence Data
- Phenotype
- Receptors, Antigen, T-Cell
- T-Lymphocyte Subsets