Article
The immunoglobulin kappa light chain repertoire expressed in the synovium of a patient with rheumatoid arthritis.
Arthritis and rheumatism - 1 Aug 1992
Lee S K, Bridges S L, Koopman W J, Schroeder H W
Abstract excerpt
OBJECTIVE: To analyze the nature of the B cell response in the synovial tissue of a patient with rheumatoid arthritis (RA). Specifically, we sought to determine if the pattern of immunoglobulin expression was consistent with polyclonal stimulation of B cells or an antigen-driven response. METHODS: We generated an unrestricted complementary DNA (cDNA) library from the diseased synovium of a rheumatoid factor...
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