Article
Distinct requirements for evoked and spontaneous release of neurotransmitter are revealed by mutations in the Drosophila gene neuronal-synaptobrevin.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Mar 1998
Deitcher D L, Ueda A, Stewart B A, Burgess R W, Kidokoro Y, Schwarz T L
Abstract excerpt
Two modes of vesicular release of transmitter occur at a synapse: spontaneous release in the absence of a stimulus and evoked release that is triggered by Ca2+ influx. These modes often have been presumed to represent the same exocytotic apparatus functioning at different rates in different Ca2+...
Topics
- Animals
- Drosophila
- Female
- Male
- Membrane Proteins
- Mutation
- Neuromuscular Junction
- Neurons
- Neurotransmitter Agents
- Paralysis
- R-SNARE Proteins
- Synapses