Influence of the β-fibrinogen-455G/A polymorphism on development of ischemic stroke and coronary heart disease.

doi:10.1016/j.thromres.2014.01.001

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Article

Influence of the β-fibrinogen-455G/A polymorphism on development of ischemic stroke and coronary heart disease.

Thrombosis research - 1 Jun 2014

Gu Lian, Liu Wenhui, Yan Yan, Su Li, Wu Guangliang, Liang Baoyun, Tan Jinjing, Huang Guihua

Abstract excerpt

BACKGROUND: Ischemic stroke (IS) and coronary heart disease (CHD) are two vascular disorders that are a common cause of death worldwide. Several studies have assessed the association of the β-fibrinogen-455G/A (FGB-455G/A) polymorphism and risk of IS and CHD, but the results are still inconsistent. Our study aimed to investigate whether the FGB-455G/A polymorphism was associated with susceptibility to IS and CHD...

Topics

Case-Control Studies
Coronary Artery Disease
Female
Fibrinogen
Genetic Predisposition to Disease
Humans
Male
Myocardial Infarction
Polymorphism, Single Nucleotide
Risk Assessment
Stroke

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Open in PubMed

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PMID: 24448059
DOI: 10.1016/j.thromres.2014.01.001

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