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Article

A MAP kinase-dependent actin checkpoint ensures proper spindle orientation in fission yeast.

Nature - 19 Jul 2001

Gachet Y, Tournier S, Millar J B, Hyams J S

Abstract excerpt

The accurate segregation of chromosomes at mitosis depends on a correctly assembled bipolar spindle that exerts balanced forces on each sister chromatid. The integrity of mitotic chromosome segregation is ensured by the spindle assembly checkpoint (SAC) that delays mitosis in response to defective spindle organisation or failure of chromosome attachment. Here we describe a distinct mitotic checkpoint in the...

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PMID: 11460168
DOI: 10.1038/35085604

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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