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Article

Orphan Nuclear Receptors: The Exotics of Xenobiotics

1 Oct 2001

Abstract excerpt

nuclear receptor constitutive androstane receptor cytochrome P450 phenobarbital pregnenolone 16α-carbonitrile pregnane X receptor rifampicin steroid and xenobiotic receptor 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene retinoid X receptor Orphan nuclear receptors (NRs)1 include gene products that are structurally related to nuclear hormone receptors but lack known physiological ligands. It has become clear that...

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PMID: 11459851
DOI: 10.1074/jbc.r100033200

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