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Article

International Union of Pharmacology. LXVI. Orphan nuclear receptors.

Pharmacological reviews - 1 Dec 2006

Benoit Gérard, Cooney Austin, Giguere Vincent, Ingraham Holly, Lazar Mitch, Muscat George, Perlmann Thomas, Renaud Jean-Paul, Schwabe John, Sladek Frances, Tsai Ming-Jer, Laudet Vincent

Abstract excerpt

Half of the members of the nuclear receptors superfamily are so-called "orphan" receptors because the identity of their ligand, if any, is unknown. Because of their important biological roles, the study of orphan receptors has attracted much attention recently and has resulted in rapid advances that have helped in the discovery of novel signaling pathways. In this review we present the main features of orphan...

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PMID: 17132856
DOI: 10.1124/pr.58.4.10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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