Article
Allelism of Saccharomyces cerevisiae gene PSO10, involved in error-prone repair of psoralen-induced DNA damage, with SUMO ligase-encoding MMS21.
Current genetics - 1 Jun 2008
Hoch Nícolas C, Santos Rafael S, Rosa Renato M, Machado Roseane M, Saffi Jenifer, Brendel Martin, Henriques João A P
Abstract excerpt
In order to extend the understanding of the genetical and biochemical basis of photo-activated psoralen-induced DNA repair in the yeast Saccharomyces cerevisiae we have identified and cloned 10 pso mutants. Here, we describe the phenotypic characterization and molecular cloning of the pso10-1 mutant which is highly sensitive to photoactivated psoralens, UV(254) (nm) radiation and the alkylating agent...
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