Article
Gene PSO5 of Saccharomyces cerevisiae, involved in repair of oxidative DNA damage, is allelic to RAD16.
Current genetics - 1 May 1995
Paesi-Toresan S O, Pich C T, Grey M, Keszenman-Pereyra D, Brendel M, Henriques J A
Abstract excerpt
The pos5-1 mutation renders Saccharomyces cerevisiae cells sensitive to DNA-damaging agents. We have isolated plasmids from a S. cerevisiae genomic library capable of restoring wild-type levels of 254-nm ultraviolet light sensitivity of the pso5-1 mutant. DNA sequence analysis revealed that the c...
Topics
- Alleles
- DNA Damage
- DNA Repair
- DNA, Fungal
- Genes, Fungal
- Genetic Complementation Test
- Genetic Linkage
- Oxidation-Reduction
- Radiation Tolerance
- Saccharomyces cerevisiae
- Ultraviolet Rays
