Article
The Saccharomyces cerevisiae gene PSO5/RAD16 is involved in the regulation of DNA damage-inducible genes RNR2 and RNR3.
Current genetics - 1 Aug 1998
Paesi-Toresan S O, Maris A F, Brendel M, Henriques J A
Abstract excerpt
The expression of beta-galactosidase from DNA damage-inducible RNR2-lacZ and RNR3-lacZ fusion constructs was compared in wild-type (WT) and pso5/rad16 mutant strains after treatment with five mutagens/oxidative stressors. While exposure to the mutagens UVC, 4NQO and H2O2 induced expression of the...
Topics
- 4-Nitroquinoline-1-oxide
- Adenosine Triphosphatases
- Artificial Gene Fusion
- DNA Damage
- DNA Repair
- Fungal Proteins
- Gene Expression
- Genes, Fungal
- Hydrogen Peroxide
- Lac Operon
- Mutation
- Oxidative Stress
- Ribonucleotide Reductases
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins