Article
Detection of novel ALAD gene polymorphisms using denaturing high-performance liquid chromatography.
Human biology - 1 Jun 2001
Niu T, Seielstad M, Zeng X, Apffel A, Li G, Hahnenberger K, Xu X
Abstract excerpt
Denaturing high-performance liquid chromatography (DH-PLC), which is based on the separation of mismatched DNA heteroduplexes, is one of the most promising techniques for detecting nucleotide polymorphisms. Lead is an important environmental toxicant that can impair the cardiovascular, central nervous, renal, reproductive, and hematologic systems. Here we compare the sensitivity and efficiency of DNA polymorphism...
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