Article
p53 mutations in chondrosarcoma.
Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Feb 1998
Terek R M, Healey J H, Garin-Chesa P, Mak S, Huvos A, Albino A P
Abstract excerpt
Chondrosarcoma is a primary bone tumor that has several different grades and variants. We evaluated 48 chondrosarcomas for p53 overexpression and p53 mutations. p53 expression was evaluated with immunohistochemistry using monoclonal antibodies PAb421, PAb1801, and PAb240. p53 mutations were ident...
Topics
- Bone Neoplasms
- Cell Differentiation
- Chondrosarcoma
- Humans
- Immunohistochemistry
- Mutation
- Polymorphism, Single-Stranded Conformational
- Sequence Analysis, DNA
- Staining and Labeling
- Tumor Suppressor Protein p53