Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rapid changes in hepatitis C virus quasispecies produced by a single dose of IFN-alpha in chronically infected patients.

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Jun 2001

Fornai C, Maggi F, Favilli F, Vatteroni M L, Pistello M, Marchi S, Ciccorossi P, Antonelli G, Bendinelli M

Abstract excerpt

The effects of a single dose of 3 international megaunits of interferon-alpha2b (IFN-alpha2b) on hepatitis C virus (HCV) load and quasispecies were examined 24 h after administration in 12 previously untreated, chronically infected patients. All patients had viremia loads appreciably reduced relative to baseline values, thus confirming that the viral load is rapidly affected by IFN-alpha2b. Five patients also...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepacivirus
Share to Hepatitis C, Chronic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interferon-alpha

Share to Interferon alpha-2

Share to Leukocytes, Mononuclear

Share to Plasma

Share to Polymorphism, Single-Stranded Conformational

Share to Viremia

Source

Identifiers

PMID: 11440639
DOI: 10.1089/107999001750277899

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rapid changes in hepatitis C virus quasispecies produced by a single dose of IFN-alpha in chronically infected patients.PMID 11440639Read ↗

Early changes in hepatitis C viral quasispecies during interferon therapy predict the therapeutic outcomeSemantic proximity Read ↗

Evolution of the hepatitis C virus second envelope protein hypervariable region in chronically infected patients receiving alpha interferon therapy.Semantic proximity Read ↗

Effect of increasing dose of interferon on the evolution of hepatitis C virus 1b quasispecies.Semantic proximity Read ↗

Dynamics of hepatitis C virus quasispecies turnover during interferon-alpha treatment.Semantic proximity Read ↗

Hepatitis C virus E2 and NS5A region variability during sequential treatment with two interferon-alpha preparations.Semantic proximity Read ↗

Evolution of viral quasispecies in interferon-treated patients with chronic hepatitis C virus infection.Semantic proximity Read ↗

Hepatitis C virus (HCV) quasispecies complexity and selection in HCV/HIV-coinfected subjects treated with interferon-based regimens.Semantic proximity Read ↗

Correlation between pre-treatment quasispecies complexity and treatment outcome in chronic HCV genotype 3a.Semantic proximity Read ↗

Assessment of hepatitis C virus quasispecies heterogeneity by gel shift analysis: correlation with response to interferon therapy.Semantic proximity Read ↗

Differences in hepatitis C virus quasispecies composition between liver, peripheral blood mononuclear cells and plasma.Semantic proximity Read ↗

Effect of retreatment with interferon alone or interferon plus ribavirin on hepatitis C virus quasispecies diversification in nonresponder patients with chronic hepatitis C.Semantic proximity Read ↗

Quasispecies heterogeneity within the E1/E2 region as a pretreatment variable during pegylated interferon therapy of chronic hepatitis C virus infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.