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Article

Dynamics of hepatitis C virus quasispecies turnover during interferon-alpha treatment.

Journal of viral hepatitis - 1 Nov 2003

von Wagner M, Lee J-H, Rüster B, Kronenberger B, Sarrazin C, Roth W K, Zeuzem S

Abstract excerpt

Interferon-alpha (IFN) has been shown to accelerate the evolution of hepatitis C virus (HCV) variants (quasispecies) in nonresponder patients. Different sensitivities of HCV variants to IFN are discussed as a possible mechanism. In the present study, quasispecies were investigated in detail by a newly established and validated direct solid-phase sequencing of the hypervariable region 1 (HVR1), during the initial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14633173
DOI: 10.1046/j.1365-2893.2003.00457.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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