Article
Differences in hepatitis C virus quasispecies composition between liver, peripheral blood mononuclear cells and plasma.
1 Jul 1997
Abstract excerpt
Hepatitis C virus (HCV) exists in vivo as a highly variable mixture of closely related genomes (quasispecies), but the pathogenetic significance of such heterogeneity is still largely unknown. To investigate this issue, we compared the composition of HCV quasispecies found in the liver, peripheral blood mononuclear cells (PBMC) and plasma of ten patients by single-strand conformation polymorphism analysis of the...
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