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Article

Effect of increasing dose of interferon on the evolution of hepatitis C virus 1b quasispecies.

Journal of medical virology - 1 Feb 2000

De Mitri M S, Mele L, Morsica G, Chen C H, Sitia G, Gramenzi A, Andreone P, Alberti A, Bernardi M, Pisi E

Abstract excerpt

The effects of interferon therapy on hepatitis C virus (HCV) genome are still controversial in terms of biological and clinical significance. Changes in the quasispecies of the hypervariable (HVR) and non-structural 5A (NS5A) regions of HCV 1b were evaluated in nine patients treated with increasing doses of interferon and five untreated controls. HCV quasispecies were analyzed in HVR and NS5A by single-strand...

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Source

Identifiers

PMID: 10596011
DOI: 10.1002/(sici)1096-9071(200002)60:2<133::aid-jmv5>3.0.co;2-q

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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