Article
A dual role of the Wnt signaling pathway during aging in Caenorhabditis elegans.
Aging cell - 1 Feb 2014
Lezzerini Marco, Budovskaya Yelena
Abstract excerpt
Wnt signaling is a major and highly conserved developmental pathway that guides many important events during embryonic and larval development. In adulthood, misregulation of Wnt signaling has been implicated in tumorigenesis and various age-related diseases. These effects occur through highly complicated cell-to-cell interactions mediated by multiple Wnt-secreted proteins. While they share a high degree of...
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