Article
Regulation of casein kinase I epsilon activity by Wnt signaling.
The Journal of biological chemistry - 26 Mar 2004
Swiatek Wojciech, Tsai I-Chun, Klimowski Laura, Pepler Andrea, Barnette Janet, Yost H Joseph, Virshup David M
Abstract excerpt
The Wnt/beta-catenin signaling pathway is important in both development and cancer. Casein kinase Iepsilon (CKIepsilon) is a positive regulator of the canonical Wnt pathway. CKIepsilon itself can be regulated in vitro by inhibitory autophosphorylation, and recent data suggest that in vivo kinase...
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