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Article

p53 and APC mutations are detectable in the plasma and serum of patients with colorectal cancer (CRC) or adenomas.

Annals of the New York Academy of Sciences - 1 Apr 2000

Gocke C D, Benko F A, Kopreski M S, McGarrity T J

Abstract excerpt

BACKGROUND: A variety of tumor-related DNA has been detected in the plasma and serum of cancer patients, including RAS, the BCL2-IgH transgene, and p53. It is not known whether the APC gene, which is frequently mutated in colorectal cancer (CRC), can be identified in the plasma of CRC patients. Similarly, it is unknown whether another tumor suppressor gene altered in CRC, p53, is detectable in people with...

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Source

Identifiers

PMID: 10818595
DOI: 10.1111/j.1749-6632.2000.tb06589.x

Genes

APC
BCL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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